The Glycoprotein VI Polyclonal Antibody, Cy3 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to GP6. This antibody recognizes Human, Mouse, and Rat antigen. The Glycoprotein VI Polyclonal Antibody, Cy3 Conjugated has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets. GPVI plays an important role in platelet procoagulant activity which may contribute to arterial and venous thrombus formation. GPVI is expressed in megakaryocytes and platelets. Patients deficient in GPVI suffer from mild hemorrhagic diathesis and their platelets fail to aggregate in response to collagen. There are three isoforms